The liver is located on the right side of the body, in the
upper abdomen. In humans, it is the second largest organ of the body, weighing
about 4 pounds (lbs.) (skin is the largest organ). Even while exposed to
tremendous potential for damage, the liver performs a multitude of essential
functions: metabolizing, detoxifying, and regenerating. It does an
extraordinary job of keeping us alive and healthy by metabolizing the food we
eat (ie, breaking it down into useful parts) and protecting us from the damaging
effects of numerous toxic compounds we are exposed to on a daily basis. Several
times each day, our entire blood supply passes through the liver. At any given
time, about a pint of blood is in the liver (or 10% of the total blood volume
of an adult) (NIDDK 2000). In addition, the liver has impressive restorative
capabilities and is the only organ in the body capable of regenerating itself
when part of it has been damaged.
Liver damage
caused by degenerative conditions is irreversible. There are no
commonly accepted, effective, conventional drug therapy regimes to prevent or reverse liver
damage. Treatment primarily consists of identifying the underlying cause(s),
determining possible steps to slow or stop progression of degeneration, and
manage symptoms. One causal factor is alcohol: stopping alcohol intake will
help stop progression. Ending the use of hepatotoxic drugs and removing sources
of environmental toxins will also stop progression. The possible presence of
metabolic diseases (eg, hemochromatosis, Wilson's disease) should be
investigated. Identifying the presence of hepatitis viruses is essential.
Because obesity plays an important role in fatty liver, attention to weight
control is essential.
Itching is a very troublesome symptom for
patients with liver disease. It is also a very difficult symptom to manage for
physicians. The reason why patients with liver disease itch is not understood.
One thought is that certain substances accumulate in the blood as a result of
liver disease and cause itching. The nature of these substances is under
investigation, but some evidence suggests that normal substances found in blood
plasma (eg, endogenous opioids known as enkaphalins) for some unknown reason
cause itching in liver disease patients.
Glutathione is involved in many cellular processes, including cell
differentiation, proliferation and apoptosis (death). The mitochondria in your
cells make “free radicals” along with the energy they produce. If you’re
deficient in Glutathione, your mitochondria are the first parts to be damaged. Unchecked free radicals also lead to
degenerative diseases and aging.
Glutathione is needed by the liver in order to carry out its detoxification
processes. all those
Glutathione is essential for our immune system function,
especially cell-mediated immunity. Infection, exercise and toxins all deplete
glutathione and can trigger mitochondrial dysfunction. This explains
why people with chronic infections may develop severe fatigue and other types
of chronic health problems. glutahtione is essential for the production
and responses of key immune system proteins like interleukin (il)-2 and
the activity of killer cells. glutahtione alsoreduces inflammation, which we’ve learned is a silent killer.
it is essential to many other processes, including cellular redox homeostasis, oxygen
transport, protection of dna, amino acid transport, protection of b12inside the cells and the removal of heavy metals.
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